Analysis of Protein Post-Translational Modification by Mass Spectrometry

Description: Editorial ReviewsFrom the Inside FlapProvides a comprehensive overview of the various ways mass spectrometry can be used for the detection and analysis of protein post-translational modificationsPost-translational modification of a protein adds significant diversity and function to the proteome. It may involve the addition of functional groups to amino acids, covalent linkage of other proteins or fatty acids, a change in the chemical nature of an amino acid or structural changes resulting from proteolytic cleavage or disulfide bridge formation. Over the last 10 years, mass spectrometry has become a critical tool in the analysis of proteins structure, quantity and modification. Of the 300 or so PTMs known, this book sets out to describe mass spectrometry-based methods for the analysis of some of the most well studied.Providing a single starting reference point for this growing and important field, with contributions from renowned experts in the analysis of all of the major PTMs and containing key background, references and summarizing the current state-of-the-art, this book is an indispensable tool for students and practitioners of protein mass spectrometry.From the Back CoverProvides a comprehensive overview of the various ways mass spectrometry can be used for the detection and analysis of protein post-translational modificationsPost-translational modification of a protein adds significant diversity and function to the proteome. It may involve the addition of functional groups to amino acids, covalent linkage of other proteins or fatty acids, a change in the chemical nature of an amino acid or structural changes resulting from proteolytic cleavage or disulfide bridge formation. Over the last 10 years, mass spectrometry has become a critical tool in the analysis of proteins structure, quantity and modification. Of the 300 or so PTMs known, this book sets out to describe mass spectrometry-based methods for the analysis of some of the most well studied.Providing a single starting reference point for this growing and important field, with contributions from renowned experts in the analysis of all of the major PTMs and containing key background, references and summarizing the current state-of-the-art, this book is an indispensable tool for students and practitioners of protein mass spectrometry.Read moreISBN-13 ‏ : ‎ 978-1119045854Item Weight ‏ : ‎ 1.53 poundsDimensions ‏ : ‎ 6.3 x 1 x 9.4 inches

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