Bioimaging in Neurodegeneration by Patricia A. Broderick (English) Paperback Boo

Description: Bioimaging in Neurodegeneration by Patricia A. Broderick, David N. Rahni, Edwin H. Kolodny Bioimaging is in the forefront of medicine for the diagnosis and helps to predict the progression of AD via mild cognitive treatment of neurodegenerative disease. Conventional magnetic impairment (MCI) studies. resonance imaging (MRI) uses interactive external magnetic fields Novel neuroimaging technologies, such as neuromolecular and resonant frequencies of protons from water molecules. imaging (NMI) with a series of newly developed BRODERICK ® However, newer sequences, such as magnetization-prepared rapid PROBE sensors, directly image neurotransmitters, precursors, acquisition gradient echo (MPRAGE), are able to seek higher and metabolites in vivo, in real time and within seconds, at separate levels of anatomic resolution by allowing more rapid temporal and selective waveform potentials. NMI, which uses an imaging. Magnetic resonance spectroscopy (MRS) images electrochemical basis for detection, enables the differentiation of metabolic changes, enabling underlying pathophysiologic neurodegenerative diseases in patients who present with mesial dysfunction in neurodegeneration to be deciphered. Neuro- versus neocortical temporal lobe epilepsy. In fact, NMI has some 1 chemicals visible with proton H MRS include N-acetyl aspartate remarkable similarities to MRI insofar as there is technological (NAA), creatine/phosphocreatine (Cr), and choline (Cho); NAA dependence on electron and proton transfer, respectively, and is considered to act as an in vivo marker for neuronal loss and/or further dependence is seen in both NMI and MRI on tissue neuronal dysfunction. By extending imaging to the study of composition such as lipids. FORMAT Paperback LANGUAGE English CONDITION Brand New Back Cover New imaging sensors, molecular probes, and neuromarkers for faster temporal resolution, smaller spatial resolution, and higher anatomic accuracy have made brain neuroimaging highly valuable in studying neuropathologies. Provocative insights into how the human brain actually works in real time and in vivo are now possible. In Bioimaging in Neurodegeneration, prominent physicians, researchers, and inventors of cutting-edge technologies review the new imaging tools available for diagnosing, treating, and discovering the underlying causes of Parkinsons and Alzheimers disease, epilepsy, and leukodystrophy. The new technologies demonstrated include novel sequences for magnetic resonance imaging (MRI), such as magnetization-prepared rapid acquisition gradient echo (MPRAGE); proton magnetic resonance spectroscopy (1H MRS); new tracers for positron emission tomography (PET) and single-photon emission tomography (SPECT), such as tropane analogs and altropane; neuromolecular imaging (NMI) of neurotransmitters directly in brain synapses of epilepsy patients with unique carbon-based electrochemical sensors; and intrinsic optical signal imaging (IOS), useful in diagnosing "spreading epileptiform depression." NMI and IOS also promise applications in intraoperative guided neurosurgery. Pediatric mitochondrial cytopathies are discussed, as well as nanotechnology, microtechnology, nanoimaging, and microimaging are presented. Devices for diagnosing tumors are also described. To enhance understanding of the potential of these developing technologies, a companion compact disk contains color versions of selected black-and-white illustrations used in the book. Authoritative and state-of-the art, Bioimaging in Neurodegeneration offers both the physician and researcher a critical survey of the best new technologies for studying neurodegeneration, as well as describing their optimal use in the diagnosis and treatment of specific neurodegenerative diseases. Table of Contents Parkinsons Disease.- Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy in Parkinsons Disease.- Positron Emission Tomography and Single-Photon Emission Tomography in the Diagnosis of Parkinsons Disease.- Positron Emission Tomography in Parkinsons Disease.- [123I]-Altropane SPECT.- Positron Emission Tomography and Embryonic Dopamine Cell Transplantation in Parkinsons Disease.- Alzheimers Disease.- Neurotoxicity of the Alzheimers ?-Amyloid Peptide.- Functional Imaging and Psychopathological Consequences of Inflammation in Alzheimers Dementia.- Neurotoxic Oxidative Metabolite of Serotonin.- Predicting Progression of Alzheimers Disease With Magnetic Resonance.- Stages of Brain Functional Failure in Alzheimers Disease.- Epilepsy.- Neocortical Epilepsy.- Pediatric Cortical Dysplasia.- Bioimaging L-Tryptophan in Human Hippocampus and Neocortex.- In Vivo Intrinsic Optical Signal Imaging of Neocortical Epilepsy.- Intraoperative Magnetic Resonance Imaging in the Surgical Treatment of Epilepsy.- Periodic Epileptiform Discharges Associated With Increased Cerebral Blood Flow.- Imaging White Matter Signals in Epilepsy Patients.- Leukodystrophy (White Matter) Diseases.- Overview of the Leukoencephalopathies.- Pyramidal Tract Involvement in Adult Krabbes Disease.- Imaging Leukodystrophies.- Advanced Magnetic Resonance Imaging in Leukodystrophies.- Childhood Mitochondrial Disorders and Other Inborn Errors of Metabolism Presenting With White Matter Disease.- Mitochondrial Disease. Review "The editors have succeeded in creating a bridge between the molecular biology of important neurodegenrative disorders and advances in brain imaging." - Journal of Neurosurgery"...highly recommended to readers who require a solid review and reference text on the state of the art in bioimaging in neurodegenrative diseases." - Annals of Neurology Long Description Bioimaging is in the forefront of medicine for the diagnosis and helps to predict the progression of AD via mild cognitive treatment of neurodegenerative disease. Conventional magnetic impairment (MCI) studies. resonance imaging (MRI) uses interactive external magnetic fields Novel neuroimaging technologies, such as neuromolecular and resonant frequencies of protons from water molecules. imaging (NMI) with a series of newly developed BRODERICK Review Quote "The editors have succeeded in creating a bridge between the molecular biology of important neurodegenrative disorders and advances in brain imaging." - Journal of Neurosurgery "...highly recommended to readers who require a solid review and reference text on the state of the art in bioimaging in neurodegenrative diseases." - Annals of Neurology Feature Includes supplementary material: sn.pub/extras Details ISBN1627038116 Year 2014 ISBN-10 1627038116 ISBN-13 9781627038119 Publisher Humana Press Inc. Series Contemporary Neuroscience Format Paperback Publication Date 2014-11-29 Short Title BIOIMAGING IN NEURODEGENERATIO Language English Media Book Imprint Humana Press Inc. Place of Publication Totowa, NJ Country of Publication United States Edited by Edwin H. Kolodny Edition 2005th UK Release Date 2014-11-29 AU Release Date 2014-11-29 NZ Release Date 2014-11-29 US Release Date 2014-11-29 Author Edwin H. Kolodny Edition Description 2005 ed. Alternative 9781588293916 DEWEY 616.804757 Audience Professional & Vocational Pages 313 Illustrations XVI, 313 p. We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:96255736;

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