Description: Biomarkers for Huntington's Disease by Elizabeth A. Thomas, Georgia M. Parkin Estimated delivery 3-12 business days Format Hardcover Condition Brand New Description This book represents the first book focused solely on biomarkers for HD and represents adistinct resource that will be informative, not only for clinicians and those involved in clinical trial design, but also for a wide range of neurodegenerative disease researchers. Publisher Description Huntingtons disease (HD) is a fatal, inherited, neurodegenerative disorder, characterized by chorea, motor instabilities, psychiatric manifestations and cognitive decline. Early genetic testing provides an opportunity for clinical interventions aimed at delaying onset and/or slowing progression of disease; however, current treatments for HD are limited, with only two FDA-approved drugs available to manage chorea. Encouragingly, however, several disease-modifying treatment approaches are in the therapeutic pipeline, with more than 200 clinical studies, and many more preclinical studies, in the works. Robust and reliable biomarkers are needed to predict disease onset, monitor disease progression and assess treatment responses. More specifically, biomarkers to stratify patients for clinical trials and biomarkers to track drug efficacy will certainly lead to improved clinical trial design and success. This book represents the first book focused solely on biomarkers for HD and represents adistinct resource that will be informative, not only for clinicians and those involved in clinical trial design, but also for a wide range of neurodegenerative disease researchers. This edited volume is written by top leaders in the field, and takes a cross-disciplinary approach to cover a broad spectrum of biomarker types, in order to provide the latest advances in the development of biochemical, molecular, imaging and digital biomarkers that have been investigated for HD. With the ultimate goal of treating patients, the development of disease-associated biomarkers has never been more important. Author Biography Elizabeth A. Thomas, Ph.D.Elizabeth A. Thomas received her Bachelors degree in biochemistry from the University of California (UC), Berkeley in 1989, and then studied at the UC Irvine, School of Medicine, receiving her Ph.D. in pharmacology in 1994. International appointments include time as an Adjunct Research Officer at the Mental Health Research Institute of Victoria in Melbourne, Australia, followed by an Honorary Senior Research Fellow at The Florey Institute of Neuroscience and Mental, Health, also in Melbourne, Australia. She is currently the laboratory director of the Institute for Interdisciplinary Salivary Bioscience Research at UC Irvine, and also holds positions of Research Professor in the Department of Neurobiology and Human Behavior at UC Irvine, and Adjunct Associate Professor in the Department of Neuroscience at the S^100 peer-reviewed publications to date, and her work has appeared in journals such as Nature Neuroscience, Proceedings of the National Academy of Sciences, Cell Stem Cell, Human Molecular Genetics, Biological Psychiatry and Molecular Psychiatry.Georgia M. Parkin, Ph.D.Georgia M. Parkin received her Bachelors degree in biochemistry from the University of Melbourne, Australia in 2011, her Masters degree in neuroscience from the University of Zurich, Switzerland in 2014, and her Ph.D. in neuroscience from the Florey Institute of Neuroscience and Mental Health, and the University of Melbourne, Australia in 2019. Her work has spanned the fields of traumatic brain injury, psychiatric illness with a focus on schizophrenia and bipolar disorder, and Huntingtons disease. Dr. Parkin is academically trained in laboratory-based research, with her past studies focusing on cell culture and mouse models, as well as human subjects and clinical patients, and involving biospecimens such as post-mortem brain tissue, blood, saliva and cerebrospinal fluid. Concurrent to, and following, completion of her Ph.D., Dr.Parkin has also specialized in clinical biomarker research, through appointments at the Murdoch Childrens Research Institute and Royal Melbourne Hospital, Australia, and the Institute for Interdisciplinary Salivary Bioscience Research at University of California, Irvine. She currently works in the Department of Neurosciences at the University of California, San Diego, and is part of the Huntingtons Disease Society of America Center of Excellence at this site. Her published work has been featured in journals including Nature Neuroscience, Neuroscience and Biobehavioral Reviews, Bipolar Disorders, International Journal of Molecular Sciences, among others; her research has also been shared by multiple news sites. Details ISBN 3031328140 ISBN-13 9783031328145 Title Biomarkers for Huntington's Disease Author Elizabeth A. Thomas, Georgia M. Parkin Format Hardcover Year 2023 Pages 475 Edition 2023rd Publisher Springer International Publishing AG GE_Item_ID:158879131; About Us Grand Eagle Retail is the ideal place for all your shopping needs! With fast shipping, low prices, friendly service and over 1,000,000 in stock items - you're bound to find what you want, at a price you'll love! Shipping & Delivery Times Shipping is FREE to any address in USA. Please view eBay estimated delivery times at the top of the listing. Deliveries are made by either USPS or Courier. We are unable to deliver faster than stated. International deliveries will take 1-6 weeks. NOTE: We are unable to offer combined shipping for multiple items purchased. This is because our items are shipped from different locations. Returns If you wish to return an item, please consult our Returns Policy as below: Please contact Customer Services and request "Return Authorisation" before you send your item back to us. Unauthorised returns will not be accepted. Returns must be postmarked within 4 business days of authorisation and must be in resellable condition. Returns are shipped at the customer's risk. We cannot take responsibility for items which are lost or damaged in transit. For purchases where a shipping charge was paid, there will be no refund of the original shipping charge. Additional Questions If you have any questions please feel free to Contact Us. Categories Baby Books Electronics Fashion Games Health & Beauty Home, Garden & Pets Movies Music Sports & Outdoors Toys
Price: 242.66 USD
Location: Fairfield, Ohio
End Time: 2025-01-03T19:16:40.000Z
Shipping Cost: 0 USD
Product Images
Item Specifics
Restocking Fee: No
Return shipping will be paid by: Buyer
All returns accepted: Returns Accepted
Item must be returned within: 30 Days
Refund will be given as: Money Back
ISBN-13: 9783031328145
Book Title: Biomarkers for Huntington's Disease
Number of Pages: Xvi, 475 Pages
Publication Name: Biomarkers for Huntington's Disease : Improving Clinical Outcomes
Language: English
Publisher: Springer International Publishing A&G
Subject: Neurology, Life Sciences / Neuroscience, Life Sciences / Anatomy & Physiology (See Also Life Sciences / Human Anatomy & Physiology), Internal Medicine
Publication Year: 2023
Item Weight: 31.7 Oz
Type: Textbook
Subject Area: Science, Medical
Author: Georgia M. Parkin
Item Length: 9.3 in
Item Width: 6.1 in
Series: Contemporary Clinical Neuroscience Ser.
Format: Hardcover
